Testing for 3017399 (ARUP) TPSAB1 Copy Number Analysis by ddPCR. Here is the link here
3.2 Incidence
~6% of caucasians of HAT
Autosomal dominant
They have increased allergies
~15% of SM have HAT
The frequency of HAT in MC disorders varies according to the diagnostic subtype of the disease.
HAT does not imply a higher risk (and severity) of anaphylaxis in mastocytosis patients in whom anaphylaxis is not part of the presenting symptoms of the disease. González-de-Olano et al. (2023)
González-de-Olano, David, Paula Navarro-Navarro, Javier I. Muñoz-González, et al. 2023. “Clinical Impact of the TPSAB1 Genotype in Mast Cell Diseases: A REMA Study in a Cohort of 959 Individuals.”Allergy 79 (3): 711–23. https://doi.org/10.1111/all.15911.